Development Of Public Policies Research Articles

Either win-win deal or exploitation? Narratives surrounding volunteering in the social scientific literature

Volunteering is an essential resource for European countries and can be an opportunity for social participation. Yet it can also lead to exploitation. Social scientific narratives on this object are important because of the role that scholars can play in the development and implementation of public policies. Drawing on the observation that older people provide a significant portion of volunteer work, this article examines to what extent and how the social scientific literature about older volunteers questions the risk of exploitation that is inherent to any form of voluntary engagement. We find that these discourses predominantly describe volunteering as a means to improve older people’s lives and as a needed contribution. Risks of exploitation are rarely addressed. To help avoid ageism in social sciences and in volunteering policies and programmes, we suggest that scholars should give more awareness to the volunteering-exploitation nexus in their studies of older volunteers.

Public Health Responses to CBRN Terrorism in the Middle East and North Africa.

Escalating global challenges such as disasters, conflict, and climate change underline the importance of addressing Chemical, Biological, Radiological, and Nuclear (CBRN) terrorism for sustainable public health strategies. This study aims to provide a comprehensive epidemiological analysis of CBRN incidents in the Middle East and North Africa (MENA) region, emphasizing the necessity of sustainable responses to safeguard healthcare infrastructures. Utilizing a retrospective approach, this research analyzes data from the Global Terrorism Database (GTD) covering the period from 2003 to 2020. The study focuses on examining the frequency, characteristics, and consequences of CBRN incidents in the MENA region to identify patterns and trends that pose significant challenges to public health systems. The analysis revealed a significant clustering of CBRN incidents in Iraq and Syria, with a predominant involvement of chemical agents. These findings indicate the extensive impact of CBRN terrorism on healthcare infrastructures, highlighting the challenges in providing immediate health responses and the necessity for long-term recovery strategies. The study underscores the need for improved healthcare preparedness, robust emergency response systems, and the development of sustainable public health policies. Advocating for international collaboration, the research contributes to the strategic adaptation of healthcare systems to mitigate the impacts of CBRN terrorism, ensuring preparedness for future incidents in the MENA region and beyond.

The prevalence of developmental defects of enamel in people with cystic fibrosis: a systematic review

BackgroundOral health impacts systemic health, individual well-being, and quality of life. It is important to identify conditions that may exacerbate oral disease to aid public health and policy development and promote targeted patient treatment strategies. Developmental defects can increase an individual’s risk of dental caries, hypersensitivity, premature tooth wear, erosion, and poor aesthetics. As part of an ongoing study assessing oral health in adults with cystic fibrosis at Cork University Dental School and Hospital, a systematic review of available literature was conducted to assess the prevalence of enamel defects in people with cystic fibrosis.AimsTo critically evaluate the literature to determine if the prevalence of developmental defects of enamel is higher in people with cystic fibrosis (PwCF).MethodsData Sources: Three online databases were searched Embase, Scopus, and Web of Science Core Collection. Studies that examined an association between cystic fibrosis and developmental defects of enamel were included in this systematic review.ResultsThe initial search identified 116 publications from the following databases Embase, Web of Science Core Collection, and Scopus. Eleven studies were included for qualitative analysis. Nine studies concluded that PwCF had a higher prevalence of enamel defects than control people and one study found no difference in cystic fibrosis (CF) status. All studies had a risk of bias that may influence study results and their interpretation.ConclusionsThe results of the systematic review show a consistent pattern that PwCF have a higher prevalence of DDE than people without CF. Genetic dysfunction, chronic systemic infections, and long-term antibiotic use are possible aetiological causes. This review highlights the need for future studies to investigate if DDEs are caused by the underlying CFTR mutation or as a consequence of disease manifestations and/or management.

Public Diplomacy and Democratic Backsliding in Turkey: A Retrospective Look at Government Investment in Soft Power

This paper discusses the development of public diplomacy policies and their implementation by the Turkish government through aggregate investment data and within the broader regional and global context in which the country’s policies evolved. Its main aim is to show how regime type is interrelated with foreign policy in general and public diplomacy as a branch of it. Turkey is a fruitful case because the country has experienced significant democratic backsliding since 2011, unlike the first period when the Justice and Development Party (henceforth AKP) came to power in 2002. The discussion over the data on budgets of various institutions responsible for adopting public diplomacy policies shows that cultural and educational public diplomacy received a major increase in investment, especially within the last six years, whereas the budgets for other institutions have fluctuated over the last ten years. Although the paper’s purpose was to provide a comprehensive picture of Turkey’s public diplomacy throughout the AKP rule since 2002, its main data source remains limited to the last decade. Thus, the availability and transparency of the data and its indication of the relationship between regime qualities and public diplomacy policies are also noted.

Age-related antibody response to Orthopoxviruses and implications for public health measures: Insights from a South Korean study

BackgroundAfter the eradication of smallpox, there have been no specific public health measures for any Orthopoxviruses (OPXVs). Therefore, it is necessary to countermeasure OPXV infections after Mpox (formerly monkeypox) occurrences, such as the latest global outbreak in 2022–2023. This study aimed to provide crucial insights for the development of effective public health policy making against mpox in populations residing in regions where the virus is not prevalent. MethodsThis study used enzyme-linked immunosorbent assays (ELISA) to examine smallpox and mpox antibodies in Koreans with three different age groups. We analyzed 56 sera obtained from a tertiary care hospital in South Korea between September 2022 and April 2023. Plasma levels of antibodies against the viral proteins of smallpox (variola cytokine response-modifying protein B) and MPXV (A29) were measured using enzyme-linked immunosorbent assays. ResultsPlasma samples from participants in their early 40 s and older exhibited higher reactivity to viral antigens than those from younger participants. Furthermore, there was a strong positive correlation in antibody positivity for the two different viruses across the sera. ConclusionsThe presence of low antibody levels in participants ˂40 years may hinder their ability to defend against OPXV. Therefore, it is imperative to implement effective public health measures to mitigate the transmission of OPXV within the community. These findings serve as fundamental information for devising strategies to combat mpox efficiently, particularly in regions where the virus is not prevalent.

National public health institutes in the Eastern Mediterranean Region: Insights from experts in the field

National public health institutes (NPHIs) are crucial to the effectiveness of public health systems, including delivering essential public health functions and generating evidence for national health policies, strategies and plans....

OPEN-ACCESS PUBLISHING IN THE FIELD OF AGING, ANTI-AGING, AND GERIATRICS

Against a background of worldwide demographic change typified by a considerable increase in elderly individuals, open-access publishing in aging, anti-aging, and geriatrics is addressed. The value of improving scientific understanding in various domains is emphasized, as is the necessity for accessible, rapidly spread knowledge to tackle the multiple difficulties posed by aging populations. The rise of open-access publishing is viewed as an innovative trend that lowers barriers to access and promotes interdisciplinary collaboration. The advantages of open access in aging research are discussed, focusing on promoting worldwide collaboration, improving visibility and citation rates, and expediting the translation of research into practical applications. Given the expanding global aged population, the article emphasizes the urgent need for extensive research and the development of public health policies to promote healthy aging. Open access is praised for its inclusive aspect, which promotes interdisciplinary collaboration and a comprehensive understanding of the aging process. Open access to aging research has a bright future, potentially expanding our understanding of the aging process, stimulating global collaboration, and influencing data-driven public health solutions. The continued evolution of open access in aging research is distinguished by collaborative efforts, ethical considerations, and a commitment to enhancing the well-being of aging people worldwide. Embracing transparency and inclusivity creates the groundwork for a future in which scientific information informs policies and behaviors that benefit future generations as they age.

Systems for rating bodies of evidence used in systematic reviews of air pollution exposure and reproductive and children’s health: a methodological survey

BackgroundTranslating findings from systematic reviews assessing associations between environmental exposures and reproductive and children’s health into policy recommendations requires valid and transparent evidence grading.MethodsWe aimed to evaluate systems for grading bodies of evidence used in systematic reviews of environmental exposures and reproductive/ children’s health outcomes, by conducting a methodological survey of air pollution research, comprising a comprehensive search for and assessment of all relevant systematic reviews. To evaluate the frameworks used for rating the internal validity of primary studies and for grading bodies of evidence (multiple studies), we considered whether and how specific criteria or domains were operationalized to address reproductive/children’s environmental health, e.g., whether the timing of exposure assessment was evaluated with regard to vulnerable developmental stages.ResultsEighteen out of 177 (9.8%) systematic reviews used formal systems for rating the body of evidence; 15 distinct internal validity assessment tools for primary studies, and nine different grading systems for bodies of evidence were used, with multiple modifications applied to the cited approaches. The Newcastle Ottawa Scale (NOS) and the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) framework, neither developed specifically for this field, were the most commonly used approaches for rating individual studies and bodies of evidence, respectively. Overall, the identified approaches were highly heterogeneous in both their comprehensiveness and their applicability to reproductive/children’s environmental health research.ConclusionEstablishing the wider use of more appropriate evidence grading methods is instrumental both for strengthening systematic review methodologies, and for the effective development and implementation of environmental public health policies, particularly for protecting pregnant persons and children.

Factors associated with hepatitis A susceptibility among men who have sex with men using HIV pre-exposure prophylaxis in Northeastern Brazil: A cross-sectional study.

Hepatitis A virus (HAV) infection has disproportionately affected more men who have sex with men (MSM), occurring in outbreaks, despite being vaccine-preventable. We determined the prevalence and factors associated with HAV susceptibility among cisgender MSM on HIV pre-exposure prophylaxis (PrEP) in Northeastern Brazil. From September 30, 2021 to June 19, 2023, 282 cisgender MSM receiving HIV PrEP were enrolled into this cross-sectional study. Sociodemographic and clinical information were collected. Blood samples were collected for screening of sexually transmitted infections (STIs) and serum samples were tested for IgM and total anti-HAV antibodies. Non-reactive results for total anti-HAV antibodies were found in 106 of 282 (37.6%) participants. Factors associated with HAV susceptibility included age <30 years (prevalence ratio [PR]: 2.02; 95% confidence interval [95% CI]: 1.61-2.53), having health insurance (PR: 1.39; 95% CI: 1.19-1.64), sex only with cisgender men (PR: 1.52; 95% CI: 1.23-1.89), non-steady partner (PR: 1.20; 95% CI: 1.01-1.43) and no lifetime history of STIs (PR: 1.25; 95% CI: 1.03-1.53). Identifying clinical correlates of HAV susceptibility in key populations is a fundamental step towards development of public policy focused on prevention, especially following the recent hepatitis A outbreak in Brazil.

Probabilistic modeling of COVID-19 events: Exploring new alpha generated family for enhanced analysis capabilities

This study explores a new family of distributions to enhance the analysis capabilities of COVID-19 events, providing valuable insights for informed decision-making and effective public health management. Accurate understanding and prediction of COVID-19 transmission patterns and their impacts are crucial in reducing the mortality rate, especially in proactive control and mitigation efforts. The proposed approach focuses on a best-fit probabilistic model that incorporates a comprehensive assessment of various statistical measures. Additionally, seven well-recognized classical point estimation methods are employed to identify the most suitable approach for assisting epidemiologists in their analysis. The study analyzes COVID-19 data from multiple countries, including the Netherlands, Mexico, the United Kingdom, China, Canada, Saudi Arabia, and Italy, considering different aspects such as mortality rates and the number of deaths. By evaluating the performance of the new alpha generated family of distributions in modeling COVID-19 events. This research contributes to the advancement of our understanding of the disease's probabilistic nature. The findings have practical implications, guiding the development of public health policies, resource allocation strategies, and intervention plans, ultimately facilitating more effective control and mitigation of COVID-19 outbreaks.

Recent developments in Behavioural Public Policy: IBPPC 2022

Recent developments in Behavioural Public Policy: IBPPC 2022

Barriers and facilitators to patient education provided by nurses: A mixed-method systematic review.

To investigate the factors that facilitate or hinder nurses in providing patient education. A mixed-method systematic review. Six databases (Cochrane Library, PubMed, EMBASE, Web of Science, MEDLINE and ERIC) were systematically searched for relevant publications. The study was conducted following the JBI for mixed-method systematic reviews, and the reporting followed the PRISMA guideline. Two researchers independently performed literature screening, literature evaluation, data extraction and synthesis. PROSPERO registration number: CRD42023427451. Twenty-six eligible articles were included, including 15 quantitative articles, 10 qualitative articles and 2 mixed-methods articles. The resultant synthesis of key findings led to the identification of these barriers and facilitators, categorised into five distinct levels: nurse-related factors, organisational factors, patient-related factors, the nurse-patient relationship and interdisciplinary collaboration. The findings highlight the factors that facilitate or hinder nurses in providing patient education, suggesting that multifaceted interventions can enhance the practice of patient education in nursing and support the development of appropriate patient education guidelines or public policies. This review delineates the facilitators and barriers influencing nurses' provision of patient education, offering an initial framework for nursing managers to craft interventions aimed at enhancing the quality of patient education provided by nurses, consequently elevating the overall quality of nursing.

Data resource profile: nutrition data in the VA million veteran program.

The Department of Veterans Affairs (VA) Million Veteran Program (MVP) nutrition data is derived from dietary food/beverage intake information collected through a semiquantitative food frequency questionnaire (SFFQ). Estimates of dietary energy, nutrient, and non-nutritive food components intakes data were derived from an extensively validated SFFQ, which assessed the habitual frequency of consumption of 61 food items, added sugar, fried food frequency, and 21 nutritional supplements over the 12 months preceding questionnaire administration. Complete nutrition data was available for 353,418 MVP participants as of 30th September 2021. Overall, 91.5% of MVP participants with nutrition data were male with an average age of 65.7 years at enrollment. Participants who completed the SFFQ were primarily White (82.5%), and Blacks accounted for 13.2% of the responders. Mean ± SD energy intake for 353, 418 MVP participants was 1428 ± 616 kcal/day, which was 1434 ± 617 kcal/day for males and 1364 ± 601 kcal/day for females. Energy intake and information on 322 nutrients and non-nutritive food components is available through contact with MVP for research collaborations at www.research.va.gov/mvp. The energy and nutrient data derived from MVP SFFQ are an invaluable resource for Veteran health and research. In conjunction with the MVP Lifestyle Survey, electronic health records, and genomic data, MVP nutrition data may be used to assess nutritional status and related risk factors, disease prevalence, and determinants of health that can provide scientific support for the development of evidence-based public health policy and health promotion programs and services for Veterans and general population.

Distribution of blood lead and cadmium levels in healthy children aged 0 to 18 years and analysis of related influencing factors in Henan, China: data findings from 2017 to 2022

BackgroundThere is still a lack of data on blood lead levels (BLLs) and blood lead levels (BLLs) in healthy children of all ages from 0 to 18 years in China. This study was performed to analyze the BLLs and BCLs in healthy children aged 0-18 years from 2017 to 2022 in urban and rural areas of Henan Province, Central China, as well as their relationships with socio-demographic variables and certain relevant exposure factors. To provide a basis for evaluating public health policy development and exposure risk management.MethodsThis was an observational study containing data from 17 prefecture-level cities in Henan, China. Blood Pb and Cd levels were determined using a triple quadrupole inductively coupled plasma mass spectrometer equipped with an autosampler. We first calculated the concentrations of Pb and Cd elements in participants of different genders, ages and years, and then created visual graphs depicting the distribution of each element in terms of gender, age and year (2017-2022). The rates between different groups were compared using the Chi-square test or Fisher exact test (if applicable). The means were compared by one-way ANOVA, medians were compared with the Kruskal-Wallis rank-sum test. Generalized linear models (GLM) were performed to estimate the effects of various factors on blood Pb and Cd concentrations in children.ResultsWe recruited a total of 25,920 children (16,142 boys and 9,778 girls) aged 0.01 to 18.00 years (2.58 (1.00,6.25)). The median of BLLs was 23.48µg/L, around 9.39% of studied children had elevated BLLs. The median of BCLs was 0.66µg/L, around 1.84% of studied children had elevated BCLs. The median blood Pb concentration was higher in boys (23.90µg/L) than in girls (22.75µg/L) (P<0.001). The median blood Pb concentration was highest in the 3-7 years group (24.51µg/L) and the median blood Cd concentration was highest in the 1-3 years group (0.66µg/L) among all age groups. Both BLLs and BCLs were substantially higher in children in 2020-2022 compared to 2017-2019. Rural children had lower BLLs and higher BCLs. The results of the generalized linear model showed that children in households using Oil, coal, pellet or other wood as a fuel for heating, children with higher frequency of exposure to tobacco smoke and beverage intake had significantly increased chances of elevated BLLs and BCLs.ConclusionsPb and Cd exposure of children in this area is relatively low, but associated risk factors continue to exist in vulnerable populations. This study is the first big data analysis of Pb and Cd in children in Henan, China, and provides baseline information for future research.

Predicting the outcome of regional development projects using machine learning

&lt;p&gt;&lt;span lang="EN-US"&gt;Morocco, in its pursuit of inclusive and sustainable territorial development, initiated the advanced regionalization experiment over six years ago. The primary challenge facing government officials today is the management of a burgeoning number of regional development projects. In this article we developed a predictive model based on artificial intelligence and Machine Learning to predict the outcomes of regional development projects, in order to identify the risks associated with their potential failure, and anticipate their impact. To accomplish this, we implemented various data mining techniques and classification algorithms. We collected and analyzed data from past and ongoing regional development projects, considering diverse factors that influence their success or failure. Through rigorous experimentation, we assessed the effectiveness of different predictive models. Our findings reveal that the Random Forest classifier stands out as an efficient algorithm for predicting the outcomes of regional development projects. This research contributes to the broader discourse on the practical implementation of artificial intelligence in public policy and regional development, showcasing its potential to optimize resource allocation, and alleviate the burden of repetitive administrative tasks for organizationsoperating with limited resources.&lt;/span&gt;&lt;/p&gt;

Development and validation of an instrument on the perception of grandparents caring for grandchildren

Objective: develop and validate an instrument to characterize sociodemographic aspects, health conditions and care among elderly grandchild carers. Method:  methodological study performed by active search on studies and instruments with the proposed theme, construction and validation of content, reliability and semantics of the instrument items. Results: the total Content Validity Index of the instrument, after validation by the judges, was 0.93%, which means that the content of the instrument makes it possible to measure what it proposes to measure. As for the reliability of the instrument, it presented an Intraclass Correlation Coefficient of 0.87 (95%CI 0.72 - 0.96), indicating that there is excellent stability of continuous variables. Cronbach's alpha presented a value of α=0.867, revealing the instrument's internal consistency. Brainstorming indicated that the items are easy to understand, with no major doubts on the part of the pilot group. Conclusion: The proposed instrument was developed and validated, and can contribute to the practice of professionals and researchers by unveiling the care relations between grandparents and grandchildren, besides supporting the development of public policies.

The Change of Public Health Emergency Policy in China: Course, Logic, and Prospect

With the frequent occurrence of various public health events, systematic analysis of public health emergency policies is urgently needed. Based on the historical institutional framework, it can be found that China's public health emergency policy has experienced four stages: slow start, rapid development, gradual adjustment and comprehensive improvement since the founding of the People's Republic of China. From the perspective of deep structure, economic level, social governance concept and scientific and technological development affect the evolution of public health emergency policy; From the perspective of path dependence, the policy is strengthened by increasing returns. From the perspective of dynamic mechanism, the interaction between key nodes and policy stakeholders promotes policy development. In the new era, the future development of China's public health emergency policy should grasp the key nodes of institutional change, enrich the policy system, improve the social participation mechanism, and encourage emergency technical innovation, and then realize the comprehensive improvement of China's public health emergency response capacity.

A GIS-based approach to assess the influence of the urban built environment on cardiac and respiratory outcomes in older adults

The impact of the urban built environment on cardiovascular and respiratory health has been studied extensively in children and adults. However, limited research exists on this topic in older adults. To fill this gap, we conducted a ten-year retrospective study of a cohort of elderly people living in Lausanne. We extracted cardiac and respiratory health outcomes of people living at the same address. A geographic information system (GIS) application was used to join spatial data between participant address and characteristics of the built environment (building age, building density, road density, proximity to vegetation and lake, elevation). To capture the impact of the urban landscape characteristics on the health of older people, the built environment descriptors, were considered alone and aggregated. Principal component analysis (PCA) was employed to resolve the multicollinearity among the built environment descriptors, while agglomerative hierarchical clustering was used to reveal underlying patterns and relationships within built environment variables. In addition, to better assess the effectiveness of ventilation in their homes, we characterized indoor air-associated mycobiomes in a representative sample of homes. This involved employing both culture-based methods and metabarcoding of the first internal transcribed spacer (ITS1) of the ribosomal DNA. The analysis revealed a significant association between exposure to the built environment as a whole and heart disease in the elderly. A higher prevalence was observed for the cluster of buildings near the lake/highway. The period of building construction showed an association with the prevalence of chronic lung disease and chronic cough, with a higher prevalence observed in houses built between 1975 and 2013. The contribution of indoor air pollution to worsening respiratory health was confirmed by higher Aspergillus spore loads and increased relative abundance of Gloeophyllum and Aureobasidium in indoor air, all of which were associated with respiratory outcomes. This research highlights the crucial influence of the built environment on the health status of the elderly population, with implications for targeted interventions and public health policy development.

Equity and gender mainstreaming in public policy: A scoping review protocol.

Despite growing attention paid to health equity and efforts to promote gender mainstreaming-a global strategy to promote gender equality-how policymakers have 'institutionalized' this in their work is less clear. Therefore, this planned scoping review seeks to search the peer-reviewed and grey literature to compile evidence on the ways in which policymakers have routinely or systematically considered equity and/or gender in their work. A scoping review will be undertaken by drawing on the PRISMA guidelines for Scoping Reviews (PRISMA-ScR). With the expert guidance of a research librarian, Ovid MEDLINE, Ovid EMBASE, PAIS Index, and Scopus databases will be searched, in addition to custom Google searches of government documents. The search will be conducted from 1995 and onwards, as there were no hits prior to this date that included the term "gender mainstream*" in these databases. The inclusion criterion is that: (i) texts must provide information on how equity and/or gender has been considered by government officials in the development of public policy in a routine or systematic manner (e.g., descriptive, empirical); (ii) both texts produced by government or not (e.g., commentary about government action) will be included; (iii) there are no restrictions on study design or article type (i.e., commentaries, reports, and other documents, would all be included); and (iv) texts must be published in English due to resource constraints. However, texts that discuss the work of nongovernmental or intergovernmental organizations will be excluded. Data will be charted by: bibliographic information, including the authors, year, and article title; country the text discussed; and a brief summary on the approach taken. This protocol was developed to improve rigour in the study design and to promote transparency by sharing our methods with the broader research community. This protocol will support a scoping review of the ways in which policymakers have routinely or systematically considered equity and/or gender in their work. We will generate findings to inform government efforts to initiate, sustain, and improve gender and equity mainstreaming approaches in policymaking.

One Health surveillance of colistin-resistant Enterobacterales in Belgium and the Netherlands between 2017 and 2019.

Colistin serves as the last line of defense against multidrug resistant Gram-negative bacterial infections in both human and veterinary medicine. This study aimed to investigate the occurrence and spread of colistin-resistant Enterobacterales (ColR-E) using a One Health approach in Belgium and in the Netherlands. In a transnational research project, a total of 998 hospitalized patients, 1430 long-term care facility (LTCF) residents, 947 children attending day care centres, 1597 pigs and 1691 broilers were sampled for the presence of ColR-E in 2017 and 2018, followed by a second round twelve months later for hospitalized patients and animals. Colistin treatment incidence in livestock farms was used to determine the association between colistin use and resistance. Selective cultures and colistin minimum inhibitory concentrations (MIC) were employed to identify ColR-E. A combination of short-read and long-read sequencing was utilized to investigate the molecular characteristics of 562 colistin-resistant isolates. Core genome multi-locus sequence typing (cgMLST) was applied to examine potential transmission events. The presence of ColR-E was observed in all One Health sectors. In Dutch hospitalized patients, ColR-E proportions (11.3 and 11.8% in both measurements) were higher than in Belgian patients (4.4 and 7.9% in both measurements), while the occurrence of ColR-E in Belgian LTCF residents (10.2%) and children in day care centres (17.6%) was higher than in their Dutch counterparts (5.6% and 12.8%, respectively). Colistin use in pig farms was associated with the occurrence of colistin resistance. The percentage of pigs carrying ColR-E was 21.8 and 23.3% in Belgium and 14.6% and 8.9% in the Netherlands during both measurements. The proportion of broilers carrying ColR-E in the Netherlands (5.3 and 1.5%) was higher compared to Belgium (1.5 and 0.7%) in both measurements. mcr-harboring E. coli were detected in 17.4% (31/178) of the screened pigs from 7 Belgian pig farms. Concurrently, four human-related Enterobacter spp. isolates harbored mcr-9.1 and mcr-10 genes. The majority of colistin-resistant isolates (419/473, 88.6% E. coli; 126/166, 75.9% Klebsiella spp.; 50/75, 66.7% Enterobacter spp.) were susceptible to the critically important antibiotics (extended-spectrum cephalosporins, fluoroquinolones, carbapenems and aminoglycosides). Chromosomal colistin resistance mutations have been identified in globally prevalent high-risk clonal lineages, including E. coli ST131 (n = 17) and ST1193 (n = 4). Clonally related isolates were detected in different patients, healthy individuals and livestock animals of the same site suggesting local transmission. Clonal clustering of E. coli ST10 and K. pneumoniae ST45 was identified in different sites from both countries suggesting that these clones have the potential to spread colistin resistance through the human population or were acquired by exposure to a common (food) source. In pig farms, the continuous circulation of related isolates was observed over time. Inter-host transmission between humans and livestock animals was not detected. The findings of this study contribute to a broader understanding of ColR-E prevalence and the possible pathways of transmission, offering insights valuable to both academic research and public health policy development.